All vaccines are by appointment on Mondays, Tuesdays, and Wednesdays from 8:30 a.m. – 4:45 p.m. To schedule an appointment for a COVID-19 vaccine, please call 660.259.4371.

Prevent. Promote. Protect.

We Serve


Cities in Missouri

The State of Missouri recently announced we are transitioning from a pandemic response to an endemic phase of COVID-19. This change to endemic does not mean the end of COVID-19; it means that the disease is here to stay, and, that we have the resources to manage the disease in our daily lives. These resources are meant to keep Missourians safe and healthy. Learn more.

We empower our communities to develop safe and healthy lifestyles.

We Provide Public Health Services You Can Depend On:

  • Immunizations – including the COVID-19 vaccine
  • STD testing and treatment
  • Vital records – birth and death certificates
  • Environmental health – food safety, drinking water, sewage, food handling classes, restaurant inspections
  • Emergency preparedness
  • School-based health services
  • WIC Program
  • Saving Smiles Dental Varnish & Sealant Program
  • Daycare inspections
  • Car seat inspections
  • Maternal child health programs
Get the Latest

Vaccine Update

COVID-19 Variants

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Missouri COVID Info

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Quick Access to Important Info

Questions? Contact Us

The Lafayette County Health Department is proud to serve area residents. If you need information that you don’t see on this site, feel free to contact us.


We all are aware of the unbelievable fight that is being waged by a killer virus, COVID 19. There are thousands of people battling this virus.

Learn how you can help!

We Value Public Health

Vision & Mission Statement

The mission of the Lafayette County Public Health Department is to empower people to develop safe and healthy lifestyles. In pursuing our mission, we value:

  • Responsiveness
  • Accountability
  • Teamwork
  • Cultural Diversity
  • Dignity, Self-worth, Individual Rights
  • Prevention and Early Intervention
  • Excellence
  • Workforce
As We Reopen

What You Need to Know

Food Truck & Fair Season

Lafayette County requires all food trucks and fair vendors to apply for a temporary food permit. Complete the permit application and return to Debbie Dreves at LCHD with the designated fee. For questions, contact Debbie at 660.259.4371, ext. 2005. Visit Food Establishments and download the permit flyer and application letter.

Business Mask Signage

As the COVID-19 pandemic increases in momentum once again, businesses have the option to require masks. We’ve provided a couple for easy access. Feel free to download. Also, we’ve provided some guidance on how to deal with masking requirements at your establishment.

Masking Health Alert

Although the previous mask requirement has been rescinded, businesses and residents are encouraged to remain cautious as cases increase in Missouri. Visit this site periodically for the latest number of COVID-19 cases and masking alerts.


547 S. Business Highway 13 Lexington, MO 64067


M-Th 8 a.m. to 5 p.m.